Masters Research Projects

Many Master of Science (Bioinformatics) students have undertaken their research projects under the direct supervision of Melbourne Bioinformatics researchers, putting them in an enviable position for entry into industry, research or a PhD.

  • Student Supervisors Thesis topicYear completed
    Matthew BrownMichael Stumpf; Grace HallNetwork inference methods for gene regulatory networks, using Baysian modelscurrent
    Lingyun DingChol-hee Jung; Steven MorganMutation interaction analysis tool in Rcurrent
    Ching-Yi PengA/Prof Bernie Pope; Jessica ChungQuantifying the Differences Between Poly-A Selection and Ribo-Depletion in RNA-Seqcurrent
    Ruixin Cai Tom Harrop Techniques for cross-species RNA seq analysis 2023
    Sangzhe Gu Chol-hee Jung Assessing the effects of incorrect metadata to the analysis of DNA methylation with the focus on the sex-labelling 2023
    Dafei Lin A/Prof Bernie Pope Assessing the effect of pseudogenes on DNA sequencing alignment and variant calling in human cancer 2021
    Jiayi Liu Chol-hee Jung Comprehensive survey of sex status of public DNA methylation datasets 2021
    Jiayu Wang A/Prof Bernie Pope Assessing the quality of structural variants in the context of DNA read alignments2021
    Tianyi Lu A/Prof Daniel Park; Khalid Mahmood Towards cost-efficient HLA sequencing screening 2019
  • Student Supervisors Thesis topicYear completed
    Zizhen HuangGrace Hall; Prof Christopher Hovens; A/Prof Bernie Pope Brain Metastases: Uncovering the role of lipid-biosynthesis pathways in tumor metastatic potential & proliferationcurrent
    Tzer Ray SuA/Prof Daniel Park; Khalid MahmoodAn exploration of cancer biology via The Cancer Genome Atlascurrent
    Alexander Nathan ThomasA/Prof Daniel Park; Khalid MahmoodAn exploration of cancer biology via The Cancer Genome Atlascurrent
    Bibo ZhaoA/Prof Daniel Park; Khalid MahmoodAn exploration of cancer biology via The Cancer Genome Atlascurrent
    Jean HoA/Prof Bernie PopeExploring rare brain mets genome somatic variant structure with common brain mets2024
    Ran LiA/Prof Bernie PopeSearch for spatial patterns in the somatic mutations (SNVs, INDELs, CNVs and SVs) in ~200 prostate cancer genomes2024
    Difei Huang A/Prof Bernie Pope Can tumour-in-normal contamination detect circulating tumour DNA and does it relate to cancer outcomes? 2023
    Senyang Xue A/Prof Daniel Park; Khalid Mahmood Tumour microenvironment and cancer outcomes 2022
    Kewei Yuan A/Prof Bernie Pope Assessing the effect of somatic mutations in cancer using reverse phase protein arrays2022
    Patrick Hawkins A/Prof Daniel Park; Khalid Mahmood Cancer Outcomes Related to Viral Agents, the Immune System, and the Tumour Microenvironment 2021
    Dongyu Li Chol-hee Jung Exploration of multi-omics prostate cancer data 2021
    Mailie Gall A/Prof Paul James; A/Prof Bernie Pope Copy number variation in Familial Colorectal Cancer Type X 2019
    Muhammad Kamran DilmirKhalid MahmoodA framework for prioritizing genomic variants and disease genes in lobular breast cancer2017
    Yu Wan Chol-hee Jung Breast cancer epigenome-wide association study 2014
  • StudentSupervisorsThesis topicYear completed
    Aoxiao GaoAllison van de Meene; Luke GandolfoIdentifying cell wall biosynthetic enzymes in grassescurrent
    Yunan GaoAllison van de Meene; Luke GandolfoIdentifying cell wall biosynthetic enzymes in grassescurrent
    Wenyuan HeAllison van de Meene; Luke GandolfoIdentifying cell wall biosynthetic enzymes in grassescurrent
    Ruxin WangChol-hee JungCharacterisation of nuclear genome encoded mitochondrial genes (MITIOME)current
    Wenyu YangA/Prof Simon Murray; Steven MorganSignalling Pathways in Oligodendrocytescurrent
  • Student Supervisors Thesis topicYear completed
    Dania Al IstwaniVicky Perreau; Steven MorganUse of public single cell RNAseq datasets to explore expression of NTRK2 transcript variants in different CNS cell typescurrent
    Chorpaka ChankaewVicky PerreauUsing public data to explore expression of GFAP transcript variants in disease and Injurycurrent
    Sally Beard Matt Wakefield Investigation of pregnancy complications: bioinformatics for therapeutic development 2020
    Yuchuan Liu Prof Judy Savige; Khalid Mahmood The genetics of inherited renGenetics of fibrillary glomerulonephritis 2019
    Steven Morgan Tara Karnezis; A/Prof Bernie Pope; A/Prof Daniel Park Identification of genetic variants associated with Lipodema project 2019
    Jianan Wang Prof Judy Savige; A/Prof Daniel Park Identification of novel genes for inherited causes of kidney failures2018
    Jonathan Reich Juan Nunez-Iglesias; Torsten Seemann Accelerating the reconstruction of brain circuits with big image analysis 2017
  • Student Supervisors Thesis topicYear completed
    Xin WangA/Prof Daniel Park; Khalid MahmoodResistance mechanisms to immunotherapy in melanomacurrent
    Ruofei Jiang A/Prof Daniel Park; Khalid Mahmood Exploring the relationship between neoantigens and immune microenvironment in cutaneous melanoma 2023
    Shijia Tang A/Prof Daniel Park; Khalid Mahmood Anti-PD1 IT in melanoma outcomes2023
    Farjana Akhter A/Prof Daniel Park; Khalid Mahmood Immune involvement in ductal and lobular breast cancer 2022
    Yizhe Mao A/Prof Daniel Park; Khalid Mahmood TCGA and Immune system 2021
    Alexander Barnett A/Prof Daniel Park; Khalid Mahmood Towards personalized cancer vaccines: modeling HLA:neoepitope binding 2020
    Peizi Chen A/Prof Daniel Park; Khalid Mahmood Somatic mutations in mismatch repair genes: an investigation using TCGA 2020
    Himanshi Arora Vicky Perreau Use of transcriptomic data and interaction networks to gain insight into addiction pathways for the prospect of future personalised medicine strategies. 2019
  • StudentSupervisorsThesis topicYear completed
    Lechuan RenGayle Philip; Vinicius Werneck SalazarComparative genomics of ocean microbial communitiescurrent
    Raquel CooperDieter BulachEstablishment of in silico virulence factor assays for use in Public Health Microbiology2022
    Qiwei HuDieter BulachMetagenomics approaches to the detection of bacterial antimicrobial resistance genes2020
    Priyanka PillaiA/Prof Sepehr Tabrizi; Dieter BulachA Whole Metagenome Sequencing approach for the investigation of the onset of bacterial vaginosis2016
    Agnes TanA/Prof Sepehr Tabrizi; Gayle PhilipChanges in microbial communities upon onset of Bacterial Vaginosis2015
    Serene SiahTorsten SeemannGenomic analysis of a novel marine mycobacterium2014
  • StudentSupervisorsThesis topicYear completed
    Andrew HarrisonA/Prof Daniel Park; Khalid MahmoodAssessing the role of protein conformations in protein variant effect prediction on protein functioncurrent
    Jessica SunA/Prof Daniel Park; Khalid MahmoodProtein structural data augmentationcurrent
    Yuanjie WangA/Prof Daniel Park; Khalid MahmoodProtein structural features for variant effect predictioncurrent
    Pengan ZhangA/Prof Daniel Park; Khalid MahmoodProtein structures data augmentationcurrent
    Chuyi WangA/Prof Daniel Park; Khalid MahmoodProtein structure features for variant effect prediction2024
    Maria OrlovskayaA/Prof Daniel Park; Khalid MahmoodMutation effect prediction for clinical diagnostics and disease gene discovery2021
    Emma DarlingA/Prof Daniel Park; Khalid MahmoodImproved mutation effect prediction via functional datasets2020