En-DIT (Endometriosis: Diagnosis, Innovation and Treatment)

Endometriosis is a common, estrogen-dependent condition associated with menstrual pain, chronic pelvic pain and infertility. The disorder is thought to affect seven to 10 per cent of women of reproductive age in Australia, increasing to 35-50 per cent of women with chronic pelvic pain and fertility problems. Medical treatment options have limited effectiveness, and surgical intervention may not prevent later recurrence. The personal and healthcare costs associated with endometriosis are high.

The En-DIT (Endometriosis: Diagnosis, Innovation and Treatment) Research Group comprises several dedicated teams of researchers, scientists, clinicians and consumers. Its research is driven by the unmet needs of consumers, and it aspires to achieve measurable and translational outcomes designed to improve the lives of endometriosis patients.

En-DIT aims to:

  • Expand our knowledge of endometriosis pathogenesis
  • Proactively educate and advocate for the implementation of research findings to the broader scientific and clinical community
  • Deliver innovative diagnostic and treatment options for endometriosis, infertility and pelvic pain
  • Translate our findings into clinical practice to achieve better patient outcomes

Jessica Chung is contributing to the group's research by developing methods to estimate menstrual cycle timing of endometrium biopsy samples based on gene expression, allowing for the identification of candidate biomarkers for endometrial disorders such as endometriosis, fibroids, and recurrent implantation failure.

For more information, see En-DIT.

CHIEF INVESTIGATORS

Prof Peter Rogers, A/Prof Martin Healey, Dr Sarah Holdsworth-Carson, Dr Jacqui Donoghue, A/Prof Helena Frawley, Dr Claudia Cheng

ORGANISATION

ROLE

University of MelbourneLEAD
Jean HailesPARTNER
Royal Women's HospitalPARTNER
Mercy HealthPARTNER
Newlife IVFPARTNER
Hadassah Medical CenterPARTNER
Western HealthPARTNER
Ramsay Health CarePARTNER
Melbourne IVFPARTNER
Healthscope HospitalsPARTNER
CabriniPARTNER
EpworthPARTNER

FUNDING

Medical Research Future Fund (MRFF) $3.9m grant (2020-2025)