SUCCEED (Systematically Understanding Comorbidities in Childhood Epileptic Encephalopathy Disorders)

Developmental and Epileptic Encephalopathies (DEEs) are devastating disorders where frequent seizures can affect a child’s development and lead to a severe disability. The SUCCEED program will leverage a novel preclinical platform that recapitulates an individual’s unique DEE to address the urgent need for more precise diagnosis and personalised treatment of DEEs. In partnership with hospitals and patient groups, the program aims to develop a portable, child-friendly device to make testing easier and less scary for kids. This is intended to help doctors diagnose DEEs sooner, prescribe the optimal therapies for individuals, and monitor if those treatments are working, improving long-term outcomes for families with these debilitating conditions.