Sex and the broken heart: sex-specific mechanisms driving heart failure
- Research Opportunity
- Honours students
- Number of Honour Places Available
- Department / Centre
- Baker Department of Cardiometabolic Health
- Baker Heart and Diabetes Institute
|Dr Alexander Pintoemail@example.com||+61385321275|
|Dr Malathi Dona||Malathi.ImiyageDona@baker.edu.au||+61385321111|
Summary Until recently the cellular composition of the heart was poorly defined. Using advanced genetic, cytometric and single cell transcriptomic approaches, our research has shed new light on the cellular constituents of the heart, demonstrating that the heart is comprised of a complex ecosystem of cell types. Furthermore, we have recently found that the cellular landscape of the heart is sexually dimorphic in terms of cell abundance, gene expression and stress responses. By combining computational biology, single-cell omics, mouse genetics and refined 2D and 3D imaging methodologies, this project aims to determine sex-specific mechanisms driving heart heart failure.
Faculty Research Themes
Child Health, Infection and Immunology
School Research Themes
Child Health in Medicine, Ageing, Cancer in Medicine, Cardiometabolic
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
For further information about this research, please contact a supervisor.
Department / Centre
Baker Department of Cardiometabolic Health
Research NodeBaker Heart and Diabetes Institute
MDHS Research library
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