MDHS researchers awarded NHMRC funding

Thirty-three MDHS researchers have been awarded funding in the current round of the NHMRC Ideas Grants Scheme.

Congratulations to the thirty-three MDHS researchers who were awarded funding in the recent round of the National Health and Medical Research Council (NHMRC) Ideas Grants Scheme. This is a wonderful result for our researchers and their innovative health projects. The research projects range from understanding the neural circuits driving stress-related eating, whether allergies start with the skin, novel therapies for slowing vision loss, optimizing diabetes therapies, mapping B-cell fate to improve humoral immunity to malaria, and the global analysis of metabolic targets in Leishmania parasites.

Below is the list of MDHS recipients and their grant titles:

Associate Professor Simon Murray

Grant title

Professor Christopher McDevitt

Harnessing structural insights to block pneumococcal manganese uptake

Professor Malcolm McConville

Global analysis of metabolic targets in Leishmania parasites

Professor John Wade

Engineering of novel insulin analogues for improved management of diabetes

Dr Ashraful Haque

Mapping B-cell fate to improve humoral immunity to malaria

Associate Professor Hayley Newton

Coxiella pathogenesis and Effector-Effector Interplay

Associate Professor Ilia Voskoboinik

Cytotoxic T cell granules – a matter of life and death

Dr Laura Edgington-Mitchell

Legumain at the cutting edge of oral cancer

Dr Kirstan Vessey

Novel therapies for slowing vision loss caused by retinal degeneration

Dr Maria del Pilar Dominguez Rodriguez

TARGETING DEREGULATED EPIGENETIC MECHANISMS IN LYMPHOMA

Associate Professor Lucy Palmer

The role of memory engrams in the cortex

Dr Magdalene Montgomery

Development of multifaceted glucose-plus therapies - A focus on Hexosaminidase A (HEXA)

Associate Professor Andrew Zalesky

Normative reference ranges for brain phenotypes in psychiatry

Associate Professor Natalie Hannan

Improving the pipeline for translation of therapies for serious complications of pregnancy

Dr Stuart McDougall

Infiltrating central command to selectively alter autonomic function

Associate Professor Daniel Scott

α1-adrenoceptor protein structures and selective tools: towards novel treatments for heart failure and Alzheimer’s disease

Dr Kevin Man

Understanding the biology of adipose tissue regulatory T cells to treat metabolic disease

Associate Professor Jason Ivanusic

On-Demand, Nanoparticle-Based Analgesia for Musculoskeletal Pain

Associate Professor Paul Neeson

TARGETING COLD TUMOURS WITH TRIPLE THERAPY

Associate Professor Michael Hildebrand

Using Cerebrospinal Fluid Liquid Biopsy for Detection of Mosaic Brain Mutations

Dr Kristin Brown

Investigating the role of cellular metabolism in regulating antigen presentation and tumour immune escape

Dr Jennifer Devlin

Targeting dysregulated transcription in cancer through Cyclin-Dependent-Kinase 11

Dr Paul Beavis

Engineering chimeric antigen receptor (CAR) T cells that induce host anti-tumour immunity

Dr Brad Gilbertson

Investigation of the structure of the influenza A virus genome and how it directs reassortment to generate novel strains

Dr Paul Beavis

CRISPR Engineering of CAR T Cells to Enhance Efficacy in Solid Tumours

Professor Wayne Phillips

Submucosal glands as the origin of Barrett’s oesophagus and oesophageal adenocarcinoma

Professor William Heath

The role of resident and circulating CD8 T cell memory in the control of liver infections

Dr Robyn Brown

Why do women overeat? Understanding the neural circuits driving stress-related eating

Associate Professor Belinda Parker

Boosting cellular immunogenicity to combat metastatic cancer

Professor Paul Gleeson

Establishment of novel, neuronal-cell based, therapeutic screens for Alzheimer’s disease using patients stem cells

Professor Gordon Lynch

Interrogating the therapeutic potential of slow muscle programming in cancer

Associate Professor Adrian Lowe

Do allergies start with the skin? A novel lipidomic analysis of early life skin to identify “high risk” children and potential targets for preventive interventions

Professor Leanne Delbridge

Towards optimizing diabetes therapies for cardioprotection: Precision approaches for women

Associate Professor Simon Murray

Promoting myelin repair in a refractory environment in vivo

Doctor Linda Fothergill

A new frontier in receptor biology relevant to treatment of
disease

Professor John Furness

A new frontier in receptor biology relevant to treatment of
disease

For more details on the Ideas Grant, visit the NHMRC website.