What kind of antibody response to women need to be protected from placental malaria?

Research Opportunity
Honours
Number of Honour Places Available
1
Department
Medicine and Radiology
Location
Royal Melbourne Hospital
Primary Supervisor Email Number Webpage
Elizabeth Aitken elizabeth.aitken@unimelb.edu.au 0383441972 Personal web page
Co-supervisor Email Number Webpage
Stephen Rogerson sroger@unimelb.edu.au Personal web page

Project Details

Pregnant women are susceptible to malaria and though we know which antigen women’s antibodies need to recognize, we don’t know the most efficient way for these antibodies to protect women.   Antibody responses can vary dramatically in nature and may confer protection in a variety of ways.  This project would involve measuring a specific aspect of the immune response towards placental malaria antigen, in samples from pregnant women and/or individuals from Phase I vaccine trials and analyzing if they are protective or if they are generated.  This will help us identify the role of individual aspects of immunity in protection, information needed to effectively design and evaluate a pregnancy-malaria vaccine. This project will involve a combination of 2 or more of the following methods solid phase immunoassays, cell based immunoassays, flow cytometry, cell culture, microcopy & statistical analysis.



Faculty Research Themes

Infection and Immunology

School Research Themes

Women's Health



Research Opportunities

Honours
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Medicine and Radiology

Research Group / Unit / Centre

Rogerson Laboratory: Pathogenesis of malaria and immunity in children and pregnant women

Research Node

Royal Melbourne Hospital

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