What is the microbiological effect of a single dose of azithromycin given in labour?

Research Opportunity
PhD, Masters by Research
Number of Master Places Available
1
Department
Paediatrics
Location
Royal Children’s Hospital/Murdoch Childrens Research Institute
Primary Supervisor Email Number Webpage
Associate Professor Catherine Satzke catherine.satzke@mcri.edu.au
Co-supervisor Email Number Webpage
Professor Fiona Russell fmruss@unimelb.edu.au
Dr Jonathan Jacobson jonathan.jacobson@mcri.edu.au

Summary Determine the effect of antibiotic administration on reducing bacterial carriage in mothers and infants in Fiji.

Project Details

Administration of azithromycin during labour can reduce maternal pathogen carriage, and lower infection risk in both mother and infant, and has considerable potential impact in resource-limited settings. Bulabula MaPei is a randomised controlled trial in Fiji, to examine the effect of a single oral dose of azithromycin given to women in labour.

In this PhD, you will use microbiological approaches to understand the benefits of this approach by determining the effect of antibiotic (compared with placebo) on bacterial carriage in both the mother and the infant. It is also important to determine whether the use of broad-spectrum antibiotics in this way might have an adverse impact, and so you will determine this by measuring antibiotic resistance in the bacterial isolates.

You will be based at the Murdoch Children’s Research Institute in the microbiology laboratory headed by A/Prof Satzke. You will also be supported through supervision by Prof Fiona Russell who is the overall lead of Bulabula MaPei, and Dr Jonathan Jacobson who is a post-doctoral scientist in microbiology. This project is based in Melbourne, and you will also have the opportunity to travel to present findings to project partners in Fiji and/or conferences.



Faculty Research Themes

Infection and Immunology

School Research Themes

Child Health in Medicine



Research Opportunities

PhD, Masters by Research
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Paediatrics

Research Node

Royal Children’s Hospital/Murdoch Childrens Research Institute

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