What do antibodies need to do to protect a woman against pregnancy-malaria?

Research Opportunity
Honours, Master of Biomedical Science
Number of Honour Places Available
2
Primary Supervisor Email Number Webpage
Dr Elizabeth Aitken elizabeth.aitken@unimelb.edu.au Personal web page
Co-supervisor Email Number Webpage
Prof Stephen Rogerson sroger@unimelb.edu.au Personal web page

Summary This project would involve measuring different kinds of antibodies towards placental malaria antigen in samples from pregnant women and/or individuals from Phase I vaccine trials, and analysing if they are protective or if they are generated. This will help us understand the types of antibodies involved in protection, information needed to effectively design and evaluate a pregnancy-malaria vaccine.

Project Details

Pregnant women are susceptible to malaria and though we know which antigen women’s antibodies need to recognise, we don’t know the most efficient way for these antibodies to protect women.  This project would involve measuring different kinds of antibodies towards placental malaria antigen in samples from pregnant women and/or individuals from Phase I vaccine trials, and analysing if they are protective or if they are generated. This will help us understand the types of antibodies involved in protection, information needed to effectively design and evaluate a pregnancy-malaria vaccine.




Research Opportunities

Honours, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.


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