Using pluripotent stem cells to model AMD
- Research Opportunity
- PhD, Masters by Research, Honours, Master of Biomedical Science
- Number of Honour Places Available
- Surgery, Ophthalmology, Royal Victorian Eye and Ear Hospital
|A/Prof Alice Pebayemail@example.com||Personal web page|
Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Virtually nothing is known about how or why retinal cells die in AMD; however, genetic background is a significant risk factor. Our research uses stem cells from patients with eye diseases to better understand the underlying cause of diseases. In this project, we will reprogram skin and hair cells from these patients with specific genetic risk associated with AMD into induced pluripotent stem cells, and then drive the stem cells to become retinal pigmented epithelial cells to create an in vitro model in which to study AMD pathogenesis. By examining how these retinal cells die, we expect to find ways to block this process, which is an important step towards developing therapies.
This project is conducted in Centre for Eye Research Australia, Neuroregeneration Unit.
School Research Themes
PhD, Masters by Research, Honours, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
For further information about this research, please contact a supervisor.
Research NodeSurgery, Ophthalmology, Royal Victorian Eye and Ear Hospital
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