Unravelling the Inflammatory Signatures of Paediatric Respiratory Disease
- Research Opportunity
- PhD students
- Department / Centre
- Royal Children’s Hospital/Murdoch Childrens Research Institute
|Dr Melanie Neelandfirstname.lastname@example.org||Personal web page|
|Prof Sarath Ranganathanemail@example.com||Personal web page|
Summary Unravelling the Inflammatory Signatures of Paediatric Respiratory Disease
Inflammation is a key aspect of the pathophysiology of many common paediatric respiratory diseases, but very little is known about the exact inflammatory pathways that define different diseases. A better understanding of the inflammatory signature of different paediatric respiratory diseases would help to identify novel therapeutic targets and predictive biomarkers.
In this PhD you will have the opportunity to work as part of a larger study that is aiming to define the inflammatory signatures of common diseases such as asthma/wheeze, acute lower respiratory tract infections, lung disease of prematurity and bronchiectasis. What is unique and world leading about this project is the use of tissue specific samples (bronchoalveolar lavage and bronchial brushings). The exact focus of the PhD can be determined, but broadly speaking your PhD would involve laboratory experience with techniques such as flow cytometry and single cell RNA sequencing, and bioinformatic analysis using multi-omic data sets.
The ideal candidate would have laboratory experience, ideally with flow cytometry or RNA sequencing, and be keen to undertake research that has a strong clinical component.
Faculty Research Themes
School Research Themes
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
For further information about this research, please contact a supervisor.
Department / Centre
Research NodeRoyal Children’s Hospital/Murdoch Childrens Research Institute
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