Unravelling the aetiology of Colonic Polyposis through multi-omic profiling
- Research Opportunity
- PhD, Masters by Research, Honours, Master of Biomedical Science
- Number of Honour Places Available
- Clinical Pathology
|A/Prof Daniel Buchananfirstname.lastname@example.org||0385597004||Personal web page|
|Dr Mark Clendenningemail@example.com||0385597006||Personal web page|
The development of a colorectal cancer (CRC) is usually preceded by pre-cursor/pre-malignant lesion called a polyp. There are two major types of polyp defined by histological features namely the adenomatous polyp and the serrated polyp. Individuals who develop 10 or more polyps throughout their colon are referred to as having polyposis, which predisposes individuals to develop CRC. Approximately 30-50% of individuals with adenomatous polyposis and the majority of individuals with Serrated Polyposis do not currently have a genetic basis identified for their disease. This project will utilise multi-omic approaches including genomics, gene and protein expression, microbiome and DNA methylation analysis to investigate the genetic basis of colonic polyposis. This project will develop expertise in genomics, molecular biology, histology, bioinformatic and statistical analysis. A stipend for this project is available to the selected student.
Faculty Research Themes
School Research Themes
PhD, Masters by Research, Honours, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
For further information about this research, please contact a supervisor.
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