Understanding Rab39b-Mediated Parkinson's Disease
- Research Opportunity
- Royal Children’s Hospital/Murdoch Childrens Research Institute
|Associate Professor Paul Lockhartemail@example.com||+61383416322||Personal web page|
|Dr Kiymet Bozaoglufirstname.lastname@example.org||Personal web page|
The recent advances in our understanding of common and disabling neurodegenerative diseases such as Parkinson and Alzheimer disease has been the result of the identification and analysis of causative mutations in families, where a genetics-based approach can be utilised to identify disease associated genes. We recently identified RAB39B as a novel gene for Parkinson's disease.
This project will characterise the gene and investigate pathogenic mechanisms underlying disease utilising molecular and cell biology techniques. Studies will utilise newly developed and unique iPSC and mouse models to perform preclinical studies to characterise the disease process and identify potential therapeutic targets.
Faculty Research Themes
School Research Themes
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
For further information about this research, please contact a supervisor.
Research NodeRoyal Children’s Hospital/Murdoch Childrens Research Institute
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