Understanding pneumococcal pathogenesis
- Research Opportunity
- PhD students
- Department / Centre
- Paediatrics
- Location
- Royal Children’s Hospital/Murdoch Childrens Research Institute
Primary Supervisor | Number | Webpage | |
---|---|---|---|
A/Prof Catherine Satzke | catherine.satzke@mcri.edu.au | Personal web page |
Co-supervisor | Number | Webpage | |
---|---|---|---|
Dr Sam Manna | sam.manna@mcri.edu.au | Personal web page |
Summary Streptococcus pneumoniae (the pneumococcus) is the most common cause of community-acquired pneumonia and a leading killer of children world-wide. However, it is also commonly found as an asymptomatic coloniser of the upper respiratory tract (carriage). Pneumococcal carriage is an important reservoir for transmission and a precursor to disease.Your research will provide new insights into how pneumococci colonise and cause disease.
Project Details
Streptococcus pneumoniae (the pneumococcus) is the most common cause of community-acquired pneumonia and a leading killer of children world-wide. However, it is also commonly found as an asymptomatic coloniser of the upper respiratory tract (carriage). Pneumococcal carriage is an important reservoir for transmission and a precursor to disease.
In this project, you will identify novel genes and characterise their role in pneumococcal carriage and/or disease. Key approaches to this project include: genetic manipulation of pneumococcal isolates, working with in vitro and/or in vivo models such respiratory cells from patients grown as air-liquid interface and mouse models, as well as microbiological and immunological analysis of local and systemic samples. Your research will provide new insights into how pneumococci colonise and cause disease.
Faculty Research Themes
School Research Themes
Research Opportunities
PhD students
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
Key Contact
For further information about this research, please contact a supervisor.
Department / Centre
Research Node
Royal Children’s Hospital/Murdoch Childrens Research InstituteMDHS Research library
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