The role of CCL17 in osteoarthritis

Research Opportunity
PhD, Masters by Research, Honours
Number of Honour Places Available
1
Number of Master Places Available
1
Department
Medicine and Radiology
Location
Royal Melbourne Hospital
Primary Supervisor Email Number Webpage
Dr Kevin Lee mingchinl@unimelb.edu.au 83443292 Personal web page
Co-supervisor Email Number Webpage
A/Prof Andrew Cook adcook@unimelb.edu.au 83443290 Personal web page

Summary Osteoarthritis (OA) is the most common form of arthritis, for which there are no adequate therapies

Project Details

We have identified a novel role for the chemokine, CCL17 which appears to be important for the development of OA and its associated pain in animal models.
The prevalence of OA is increasing due to increased obesity in our population. In this project you will use models of obesity-induced OA to investigate how CCL17 is active in pain and disease development and whether blockade of the pathway at different stages is able to halt disease progression. A variety of skills will be acquired including induction of animal models, histology, gene expression analysis and FACS analysis.


School Research Themes

Musculoskeletal



Research Opportunities

PhD, Masters by Research, Honours
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Medicine and Radiology

Research Node

Royal Melbourne Hospital

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