The role of CCL17 in osteoarthritis
- Research Opportunity
- PhD students, Masters by Research
- Department / Centre
- Medicine
- Location
- Royal Melbourne Hospital
| Primary Supervisor | Number | Webpage | |
|---|---|---|---|
| Dr Kevin Lee | mingchinl@unimelb.edu.au | 83443292 | Personal web page |
| Co-supervisor | Number | Webpage | |
|---|---|---|---|
| A/Prof Andrew Cook | adcook@unimelb.edu.au | 83443290 | Personal web page |
Summary Osteoarthritis (OA) is the most common form of arthritis, for which there are no adequate therapies
Project Details
We have identified a novel role for the chemokine, CCL17 which appears to be important for the development of OA and its associated pain in animal models.
The prevalence of OA is increasing due to increased obesity in our population. In this project you will use models of obesity-induced OA to investigate how CCL17 is active in pain and disease development and whether blockade of the pathway at different stages is able to halt disease progression. A variety of skills will be acquired including induction of animal models, histology, gene expression analysis and FACS analysis.
School Research Themes
Research Opportunities
PhD students, Masters by Research
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
Key Contact
For further information about this research, please contact a supervisor.
Department / Centre
Research Node
Royal Melbourne HospitalMDHS Research library
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