The development of anti-NPY1 receptor antibodies for research into and treatment of cardiovascular diseases and cancer

Research Opportunity
PhD
Department
Medicine and Radiology
Location
Austin Health
Primary Supervisor Email Number Webpage
Dr Peter J Wookley pwookey@unimelb.edu.au +61 (03) 9496 3584 Personal web page

Summary Research into the developement of an immunotoxin or imaging reagent for potential treatment or imaging of CVD and breast cancer respectively.

Project Details

NPY is an important hormone and via one of its targets, NPY1 receptor, induces vasoconstriction and thickening of the neo-intima in cardiovascular disease (CVD). This receptor is also expressed by cancer cells of the breast. An anti-human NPY1 receptor antibody has been developed against a unique target in the extracellular domain of the receptor. This antibody will be developed as an immunotoxin or imaging reagent for potential treatment or imaging of CVD and breast cancer respectively.



Faculty Research Themes

Cancer

School Research Themes

Cancer in Medicine, Cardiometabolic



Research Opportunities

PhD
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Medicine and Radiology

Research Group / Unit / Centre

Cardiovascular and Tumourivascular Laboratory

Research Node

Austin Health

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