The cardiometabolic legacy of SARS-CoV-2 in longitudinal adolescents

Research Opportunity
PhD students
Department
Paediatrics
Location
Royal Children’s Hospital/Murdoch Childrens Research Institute
Primary Supervisor Email Number Webpage
Prof David Burgner david.burgner@mcri.edu.au 03 99366730
Co-supervisor Email Number Webpage
Assoc Prof Kirsten Perrett kirsten.perrett@mcri.edu.au

Summary The legacy of COVID-19, especially on the cardiovascular system is increasingly recognised. This exciting cohort study of adolescents will investigate the cardiometabolic legacy of SARS-CoV-2 infection.

Project Details

Summary: SARS-CoV-2 is a respiratory virus that hasn’t read the textbook on how it should behave; acute COVID-19 appears to be a disease of blood vessels as much as of the respiratory tract. There is also concern regarding the long-term effects of acute SARS-COv-2 infection, with increasing reports of protracted symptoms (‘long COVID’) and increased risk of cardiovascular disease (CVD). This project will address the effects of COVID-19 on the cardiovascular and metabolic (cardiometabolic) health of adolescents. This exciting innovative project will focus on the newly established YoungLives cohort of over 1000 population-representative adolescents, who will have a detailed non-invasive assessments and extensive metabolomic profiling at recruitment and again 12 months later. The findings will have immediate translational importance and will inform prevention, interventions and policy.

Project Description:

The successful applicant will join a friendly, dynamic multidisciplinary team (including other PhD students working on the immunological and psychosocial aspects of the YoungLives cohort, who are academic paediatricians, research scientists, and epidemiologists. The candidate will analyse cardiometabolic and laboratory data collected at recruitment, and undertake training to participate in the ongoing assessment of the participants. The project combines hands-on clinical research, laboratory work, and data analysis and interpretation. The project would suit a clinician (e.g. paediatrician, infectious diseases, cardiologist, endocrinologist) or a scientist with an interest and some content knowledge in these areas. Full training of cardiometabolic assessments and other key skills will be given. Excellent people skills are essential and some experience of data management and statistical analysis would be beneficial. The successful candidate is expected to be competitive for own scholarship funding (APA or similar). Top-up funding may be available.

Interested?  Please contact Dave Burgner (david.burgner@mcri.edu.au) for an informal discussion. Please include your current CV and academic transcript with your email.



Faculty Research Themes

Child Health, Infection and Immunology

School Research Themes

Child Health in Medicine, Cardiometabolic



Research Opportunities

PhD students
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Paediatrics

Research Node

Royal Children’s Hospital/Murdoch Childrens Research Institute

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