The blood pressure drop makes you fall

Research Opportunity
PhD, Masters by Research, Honours, Master of Biomedical Science
Number of Honour Places Available
Medicine and Radiology
Royal Melbourne Hospital
Primary Supervisor Email Number Webpage
Dr. Julian Sacre 0393422635 Personal web page
Co-supervisor Email Number Webpage
Prof Andrea Maier Personal web page

Project Details

(Initial) orthostatic hypotension ((i)OH) is highly prevalent in older adults, especially in those with one or more chronic diseases. iOH is defined as a blood pressure decrease(BP) of 40 mmHg systolic blood pressure (SBP) and/or 20 mmHg diastolic blood pressure (DBP) within 15 seconds after standing up, whereas OH is classically defined as a drop in BP of at least 20 mmHg of SBP and/or 10 mmHg of DBP at 1 and 3 minutes after standing up. iOH has been shown to be most predictive for balance impairment, increased self-reported impaired standing balance and falls in geriatric outpatients. While OH diagnostics are occasionally performed in clinical practice using a sphygmomanometer, continuously measured blood pressure measurements using beat to beat analyses has not entered routine geriatric care yet. Two student positions are available:

Aim project 1: Define the determinates of iOH and OH and consequences of iOH and OH in geriatric outpatients using an existing databases and ongoing cohort study.

Aim project 2: Analysis of effectiveness of non-pharmacological and pharmacological interventions to counteract iOH and OH in geriatric patients.

Prerequisite: involvement in ongoing clinical data collection, epidemiological/statistical skills, intention to write a journal article, good communication skills, capacity to work in a multidisciplinary team, pleasure to work with patients.

School Research Themes

Ageing, Cardiometabolic , Musculoskeletal

Research Opportunities

PhD, Masters by Research, Honours, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.


Medicine and Radiology

Research Node

Royal Melbourne Hospital

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