Symptom comorbidity networks in psychiatry

Research Opportunity
PhD students, Masters by Research, Post Doctor Researchers
Department / Centre
Psychiatry
Location
Royal Melbourne Hospital
Primary Supervisor Email Number Webpage
Dr Vanessa Cropley vcropley@unimelb.edu.au 83441876 Personal web page
Co-supervisor Email Number Webpage
Associate Professor Andrew Zalesky azalesky@unimelb.edu.au +61390357747 Personal web page

Summary Investigate causal links between psychiatric symptoms and cognition across mental illnesses

Project Details

Network theories of psychopathology suggest that psychopathology is the result of cyclic and causal relationships between individual symptoms, which may also be influenced by distinct environmental, biological or clinical factors. For example, a network framework might identify that a certain symptom (e.g. anxiety) triggers other symptoms (e.g. paranoia), that certain symptoms reinforce each other through feedback systems (e.g. sleep disturbance leading to worry, and worry leading to sleep disturbance), or indirectly through a third symptom (e.g. sleep disturbance influencing depression through worry), and that certain symptoms (e.g. inattention or arousal) may be particularly important, connecting to a number of different symptoms in a network. These models have important implications for understanding unique and causal relations between symptoms or other psychobiological factors, and for identifying potential symptoms for intervention.

Early-life adversity or childhood trauma is a well-known risk factor for psychopathology, including the development and course of psychotic disorders. Network analysis provides an advanced method to understand the relationship between different forms of early-life adversity and psychotic symptoms in young people.

Check out our lab website for further details: www.sysneuro.org

Further research and key questions

  • Understand causal links between psychopathology and environmental factors, including childhood trauma and early-life adversity
  • Identify modifiable risk and resilience factors that exert a causal influence on psychopathology


Faculty Research Themes

School Research Themes

Neuroscience & Psychiatry



Research Opportunities

PhD students, Masters by Research, Post Doctor Researchers
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department / Centre

Psychiatry

Research Node

Royal Melbourne Hospital

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