Studying novel proteins in preeclampsia

Research Opportunity
PhD students, Honours students
Number of Honour Places Available
1
Department / Centre
Obstetrics and Gynaecology
Location
Royal Melbourne Hospital
Primary Supervisor Email Number Webpage
Associate Professor Tu'uhevaha Kaitu'u-Lino t.klino@unimelb.edu.au 03 8458 4355 Personal web page
Co-supervisor Email Number Webpage
Associate Professor Natalie Hannan nhannan@unimelb.edu.au
Professor Stephen Tong stong@unimelb.edu.au

Summary This project will involve laboratory studies of novel placental proteins that we have identified may play a role in the pathogenesis of preeclampsia.

Project Details

Preeclampsia is a serious complication of pregnancy. It is characterised by maternal hypertension culminating from significant blood vessel damage. The placental pathogenesis of preeclampsia is still poorly understood and there are currently no efficacious treatments to halt disease progression. For survivors, preeclampsia imparts life-long health decrements including increased risk of cardiovascular disease.

As part of our diagnostics screening, we have identified a panel of novel placental proteins deranged in the maternal blood stream preceding preeclampsia diagnosis. We believe that at least some of these proteins may play a role in the pathogenesis of this serious disorder.

This project will involve laboratory studies to begin to tease apart the role and contribution of these novel proteins to disease pathogenesis using a pipeline of experimental studies specifically designed to study preeclampsia.



Faculty Research Themes

Child Health

School Research Themes

Child Health in Medicine, Women's Health



Research Opportunities

PhD students, Honours students
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department / Centre

Obstetrics and Gynaecology

Research Node

Royal Melbourne Hospital

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