Stroke assessment with Diffusion Kurtosis Imaging (DKI)

Research Opportunity
PhD, Masters by Research, Master of Biomedical Science
Department
Medicine and Radiology
Location
Royal Melbourne Hospital
Primary Supervisor Email Number Webpage
Dr Vijay Venkatraman vijay.venkatraman@unimelb.edu.au 0383440401 Personal web page
Co-supervisor Email Number Webpage
Prof Roland Bammer roland.bammer@unimelb.edu.au Personal web page

Project Details

Quantitative measure of the non-Gaussianity of the diffusion process in both white and grey matter is critical measure that needs further exploration. Interestingly, preliminary human and animal stroke DKI studies have demonstrated that abnormalities apparent on images of the DKI metric were not as distinct and/or apparent on DWI or ADC images. Ischemia is found to preferentially exert a larger effect on the intra- than extra-axonal microenvironment of WM, consistent with a proposed mechanism of axonal beading. The multi-band accelerated EPI sequences have shown utility in the clinic. This project will explore clinical utility of accelerated DKI in stroke assessment using multimodal imaging measures including CT perfusion.

We are looking for PhD (1 position available) and Master of Science (2 positions available) to work on this project. The students will be mentored and work within a multidisciplinary team in the Royal Melbourne Hospital, Florey Institute of Neuroscience and Mental Health, and University of Melbourne as well as other collaborators (in Melbourne and internationally). Additional top-up PhD scholarship will be available for qualified students. The specific details of the project will be discussed with interested candidates. Publication of results is expected at the end of the project for Masters and PhD students.



Faculty Research Themes

Neuroscience



Research Opportunities

PhD, Masters by Research, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Medicine and Radiology

Research Group / Unit / Centre

Neuroimaging

Research Node

Royal Melbourne Hospital

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