Short course antibiotic therapy for acute septic arthritis and haematogenous osteomyelitis in children

Research Opportunity
PhD, Masters by Research
Department
Paediatrics
Location
Royal Children’s Hospital/Murdoch Childrens Research Institute
Primary Supervisor Email Number Webpage
Dr Amanda Gwee amanda.gwee@rch.org.au 9345 5522 Personal web page
Co-supervisor Email Number Webpage
Prof Nigel Curtis nigel.curtis@rch.org.au 93456366 Personal web page

Summary This is a randomised factorial design non-inferiority trial of short course antibiotic therapy for children with acute septic arthritis and osteomyelitis.

Project Details

Antibiotic treatment of septic arthritis and osteomyelitis in children traditionally requires a minimum of 2-4 days of IV therapy followed by oral therapy for 3 weeks. However, a previous studies in children with bone and joint infections found that there was no difference in cure between 2 and 3 weeks of oral therapy. This is a randomised factorial design non-inferiority trial of short course antibiotic therapy for children with acute septic arthritis and osteomyelitis.

Inclusion criteria: Children 1-9 years with acute haematogenous septic arthritis or osteomyelitis.
Primary end points: Proportion of children with complete recovery at 6 weeks defined by no symptoms or signs of acute haematogenous osteomyelitis or septic arthritis.



Faculty Research Themes

Child Health

School Research Themes

Child Health in Medicine



Research Opportunities

PhD, Masters by Research
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Paediatrics

Research Node

Royal Children’s Hospital/Murdoch Childrens Research Institute

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