Short course antibiotic therapy for acute septic arthritis and haematogenous osteomyelitis in children
- Research Opportunity
- PhD students, Masters by Research
- Department / Centre
- Royal Children’s Hospital/Murdoch Childrens Research Institute
|Dr Amanda Gweeemail@example.com||9345 5522||Personal web page|
|Prof Nigel Curtisfirstname.lastname@example.org||93456366||Personal web page|
Summary This is a randomised factorial design non-inferiority trial of short course antibiotic therapy for children with acute septic arthritis and osteomyelitis.
Antibiotic treatment of septic arthritis and osteomyelitis in children traditionally requires a minimum of 2-4 days of IV therapy followed by oral therapy for 3 weeks. However, a previous studies in children with bone and joint infections found that there was no difference in cure between 2 and 3 weeks of oral therapy. This is a randomised factorial design non-inferiority trial of short course antibiotic therapy for children with acute septic arthritis and osteomyelitis.
Inclusion criteria: Children 1-9 years with acute haematogenous septic arthritis or osteomyelitis.
Primary end points: Proportion of children with complete recovery at 6 weeks defined by no symptoms or signs of acute haematogenous osteomyelitis or septic arthritis.
Faculty Research Themes
School Research Themes
PhD students, Masters by Research
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
For further information about this research, please contact a supervisor.
Department / Centre
Research NodeRoyal Children’s Hospital/Murdoch Childrens Research Institute
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