Short course antibiotic therapy for acute septic arthritis and haematogenous osteomyelitis in children
- Research Opportunity
- PhD, Masters by Research
- Royal Children’s Hospital/Murdoch Childrens Research Institute
|Dr Amanda Gweeemail@example.com||9345 5522||Personal web page|
|Prof Nigel Curtisfirstname.lastname@example.org||93456366||Personal web page|
Summary This is a randomised factorial design non-inferiority trial of short course antibiotic therapy for children with acute septic arthritis and osteomyelitis.
Antibiotic treatment of septic arthritis and osteomyelitis in children traditionally requires a minimum of 2-4 days of IV therapy followed by oral therapy for 3 weeks. However, a previous studies in children with bone and joint infections found that there was no difference in cure between 2 and 3 weeks of oral therapy. This is a randomised factorial design non-inferiority trial of short course antibiotic therapy for children with acute septic arthritis and osteomyelitis.
Inclusion criteria: Children 1-9 years with acute haematogenous septic arthritis or osteomyelitis.
Primary end points: Proportion of children with complete recovery at 6 weeks defined by no symptoms or signs of acute haematogenous osteomyelitis or septic arthritis.
Faculty Research Themes
School Research Themes
PhD, Masters by Research
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Research NodeRoyal Children’s Hospital/Murdoch Childrens Research Institute
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