Serotonin in epilepsy
- Research Opportunity
- PhD, Masters by Research, Honours, Master of Biomedical Science
- Project Status
- Medicine and Radiology
- Royal Melbourne Hospital
|Nigel Jones||Personal web page|
Any type of brain injury can result in epilepsy, a chronic neurological condition associated with seizures or ‘fits’. The pathological processes occurring in the brain which drive the development of epilepsy following brain injury are not clear, but certain drugs acting at serotonin receptors, including SSRI antidepressants, accelerate these processes.
Using animal models, this project will investigate serotonin signalling in epilepsy, and attempt to understand why SSRIs accelerate the development of disease following injury. We will utilise a variety of techniques, including assessment of serotonin levels, molecular consequences of serotonin activity, immunocytochemical identification of serotonin receptors, and pharmacological manipulation of the serotonin system, all in the context of epilepsy.
Faculty Research Themes
School Research Themes
PhD, Masters by Research, Honours, Master of Biomedical Science
Graduate Research Students who are interested in joining this project will need to consider their elegibility as well as other Graduate Research requirements before contacting the supervisor of this research
For further information about this research, please contact a supervisor.
Research Group / Unit / Centre
Research NodeRoyal Melbourne Hospital
MDHS Research library
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