Prefrontal cortex, sympathetic activity and blood pressure regulation
- Research Opportunity
- Honours students
- Number of Honour Places Available
- Department / Centre
- Baker Department of Cardiometabolic Health
- Baker Heart and Diabetes Institute
|Dr Tye Dawoodfirstname.lastname@example.org||8532 1868|
|Professor Vaughan Macefieldemail@example.com||8532 1866|
Summary There is a need to improve our understanding of how the brain interacts with other systems in the body to control blood pressure, so as to tailor more effective treatments. The sympathetic nervous system is known to play a critical role in blood pressure regulation. We have shown that activity in the prefrontal cortex is functionally coupled to bursts of muscle sympathetic nerve activity (MSNA), indicating that it could contribute to sympathetic outflow and, hence, the control of blood pressure. In this study, we will test the direct effect of prefrontal cortex stimulation on modulation of MSNA and blood pressure modification.
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Department / Centre
Research NodeBaker Heart and Diabetes Institute
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