Pharmacological approaches to food craving

Research Opportunity
PhD, Masters by Research, Honours, Master of Biomedical Science
Number of Honour Places Available
1
Number of Master Places Available
1
Department
Medicine and Radiology
Location
Austin Health
Primary Supervisor Email Number Webpage
Dr Priya Sumithran priyas@unimelb.edu.au 94962375 Personal web page
Co-supervisor Email Number Webpage
Dr Robyn Brown robyn.brown@florey.edu.au 9035 6592 Personal web page

Summary This study will examine the effect of topiramate on self-reported cravings and objective measures of autonomic nervous system activation in response to palatable foods in people with obesity.

Project Details

The currently available pharmacological treatments for obesity work primarily by reducing hunger and increasing satiety (fullness). However, we eat not only to satisfy our hunger, but in response to many other motivations including hedonic (reward) factors, food cravings, stress and emotions.

Topiramate is an anticonvulsant medication, which suppresses cravings for alcohol and other substances. It is used off-label for appetite reduction and binge eating, but there are few studies that have examined exactly how topiramate affects eating behaviours. This study will examine the effect of topiramate on self-reported cravings and objective measures of autonomic nervous system activation in response to palatable foods in people with obesity.

This study may lead to clinical trials of this agent as a treatment for disordered eating.



Faculty Research Themes

Neuroscience

School Research Themes

Neuroscience & Psychiatry, Cardiometabolic



Research Opportunities

PhD, Masters by Research, Honours, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Medicine and Radiology

Research Node

Austin Health

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