Neuropathological MRI: informing in-vivo brain imaging with ultra-high resolution MRI and histology

Research Opportunity
PhD, Masters by Research
Medicine and Radiology
Florey Institute of Neuroscience & Mental Health
Primary Supervisor Email Number Webpage
Dr Scott Kolbe +61 3 83441915 Personal web page

Project Details

MRI is being used extensively to detect neuropathological changes in brain diseases. However, the basis of the MRI signal often makes it difficult to interpret the precise neuropathologies being seen radiologically.

This project involves ultra-high resolution MRI scanning of post-mortem human brain tissue using our 7 Tesla human research scanner. Tissue will then be analysed using a range of histological and analytical chemistry techniques to identify sources of variation in MRI signals. In particular we are interested in using MRI to detect the presence of metals such as iron that is known to be involved in neurodegeneration.

Faculty Research Themes


School Research Themes

Neuroscience & Psychiatry

Research Opportunities

PhD, Masters by Research
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.


Medicine and Radiology

Research Node

Florey Institute of Neuroscience & Mental Health

MDHS Research library
Explore by researcher, school, project or topic.