Nephrotoxicity screening using stem cell-derived proximal tubules
- Research Opportunity
- PhD students
- Department / Centre
- Paediatrics
- Location
- Royal Children’s Hospital/Murdoch Childrens Research Institute
| Primary Supervisor | Number | Webpage | |
|---|---|---|---|
| Prof Melissa Little | melissa.little@mcri.edu.au | Personal web page |
| Co-supervisor | Number | Webpage | |
|---|---|---|---|
| Dr Jessica Vanslambrouk | jessica.vanslambrouk@mcri.edu.au |
Summary Nephrotoxicity screening using stem cell-derived proximal tubules
Project Details
The kidney is a major target for drug-induced toxicity, however existing kidney epithelial cell lines in culture are very poor replicas of the proximal tubule in vivo. We have developed a method for generating complex multicellular 3D human kidney models in vitro using human pluripotent stem cells. This project will investigate how to use these as a platform for the screening of drug toxicity in vitro.
Faculty Research Themes
School Research Themes
Research Opportunities
PhD students
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
Key Contact
For further information about this research, please contact a supervisor.
Department / Centre
Research Node
Royal Children’s Hospital/Murdoch Childrens Research InstituteMDHS Research library
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