Multimodal imaging measures to improve dementia diagnosis

Research Opportunity
PhD, Masters by Research, Master of Biomedical Science, Post Doctor Research
Number of Master Places Available
1
Department
Medicine and Radiology
Location
Royal Melbourne Hospital
Primary Supervisor Email Number Webpage
Dr Vijay Venkatraman vvenkatraman@unimelb.edu.au Personal web page
Co-supervisor Email Number Webpage
Prof Patricia Desmond Patricia.Desmond@mh.org.au Personal web page
Prof. Roland Bammer roland.bammer@unimelb.edu.au

Summary The aim of this study is to study the influence morphological and longitudinal measures to improve dementia diagnosis.

Project Details

Mild cognitive impairment (MCI) is generally regarded as the prodromal stage of Alzheimer’s disease. Magnetic resonance imaging (MRI) is used to extract different indexes from various morphological analyses that reflect intrinsic properties of the cerebral cortex. The best algorithms have yielded an accuracy of 63% and an AUC of 78.8%. Different indexes can be extracted from various morphological analyses and used in machine learning approaches. Further, multimodal imaging measures such as PET, longitudinal imaging measures, and cognitive measures can also be used to improve the dementia diagnosis.

The current study will use imaging and clinical data from a publicly available dataset such as The Australian Imaging Biomarkers and Lifestyle Study of Ageing (AIBL). The aim of this study is to study the influence morphological and longitudinal measures to improve dementia diagnosis.  The student will be responsible for the development of the proposal and refinement of study hypotheses, conducting a literature review, processing of brain imaging scans and performing statistical analyses. Publication of results is expected at the end of the project.



Faculty Research Themes

Neuroscience

School Research Themes

Neuroscience & Psychiatry, Ageing



Research Opportunities

PhD, Masters by Research, Master of Biomedical Science, Post Doctor Research
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Medicine and Radiology

Research Node

Royal Melbourne Hospital

MDHS Research library
Explore by researcher, school, project or topic.