Molecular and biochemical analysis of novel disease variants in neurodevelopmental disorders

Research Opportunity
Honours students, Master of Biomedical Science
Number of Honour Places Available
1
Number of Master Places Available
1
Department / Centre
Medicine and Radiology
Location
Florey Institute of Neuroscience & Mental Health
Primary Supervisor Email Number Webpage
A/Prof Jess Nithianantharajah jess.n@florey.edu.au
Co-supervisor Email Number Webpage
Dr Daniel Scott daniel.scott@florey.edu.au

Summary The Synapse Biology & Cognition Laboratory is focused on understanding the critical role synaptic genes and proteins play in establishing and regulating the coordinated wiring and connectivity in the brain, that enables complex cognition and higher order processing in the healthy brain, and in mental disorders where these processes go awry. This project will use advanced protein binding and stability assays to measure the structural and functional impacts of novel synapse gene mutations identified in neurodevelopmental disorders including Autism Spectrum Disorder, Intellectual Disability and schizophrenia.

Project Details

The Synapse Biology & Cognition Laboratory is focused on understanding the critical role synaptic genes and proteins play in establishing and regulating the coordinated wiring and connectivity in the brain, that enables complex cognition and higher order processing in the healthy brain, and in mental disorders where these processes go awry. This project will use advanced protein binding and stability assays to measure the structural and functional impacts of novel synapse gene mutations identified in neurodevelopmental disorders including Autism Spectrum Disorder, Intellectual Disability and schizophrenia.



Faculty Research Themes

Neuroscience

School Research Themes

Neuroscience & Psychiatry



Research Opportunities

Honours students, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department / Centre

Medicine and Radiology

Research Node

Florey Institute of Neuroscience & Mental Health

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