Microbial changes following pneumococcal conjugate vaccination

Research Opportunity
PhD students
Department / Centre
Paediatrics
Location
Royal Children’s Hospital/Murdoch Childrens Research Institute
Primary Supervisor Email Number Webpage
A/Prof Catherine Satzke catherine.satzke@mcri.edu.au Personal web page
Co-supervisor Email Number Webpage
Dr Laura Boelsen laura.boelsen@mcri.edu.au

Summary Pneumococci are a major global pathogen. Pneumococcal conjugate vaccines (PCVs) protect against a subset of pneumococcal serotypes. Introduction of PCVs result in major changes to pneumococcal epidemiology and to the microbiota more broadly. In this project, you will examine nasopharyngeal samples and isolates collected from children from vaccine studies in low-income settings from the Asia-Pacific region. You will apply traditional and molecular microbiology approaches including culture and serotyping, qPCR, DNA microarray, whole-genome sequencing and antimicrobial resistance testing. Your results will inform vaccine strategies world-wide.

Project Details

Pneumococci are a major global pathogen. Pneumococcal conjugate vaccines (PCVs) protect against a subset of pneumococcal serotypes. Introduction of PCVs result in major changes to pneumococcal epidemiology and to the microbiota more broadly. In this project, you will examine nasopharyngeal samples and isolates collected from children from vaccine studies in low-income settings from the Asia-Pacific region. You will apply traditional and molecular microbiology approaches including culture and serotyping, qPCR, DNA microarray, whole-genome sequencing and antimicrobial resistance testing. Your results will inform vaccine strategies world-wide. 


Faculty Research Themes

School Research Themes



Research Opportunities

PhD students
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department / Centre

Paediatrics

Research Node

Royal Children’s Hospital/Murdoch Childrens Research Institute

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