Massively Parallel Optical Imaging of Cognition Events in Neuronal Networks in Freely Behaving Mice

Research Opportunity
PhD students, Masters by Research, Honours students, Master of Biomedical Science
Number of Honour Places Available
2
Number of Master Places Available
1
Department / Centre
Medicine and Radiology
Location
Royal Melbourne Hospital
Primary Supervisor Email Number Webpage
Dr Chris French frenchc@unimelb.edu.au 8344 3276 Personal web page

Project Details

We have recently implemented for the first time in Australia the “miniscope” technique (see http://miniscope.org/index.php/Main_Page, and see our setup in https://ndl-lab.org/), in which we put small fluorescent microscopes into mouse brains and observe the activity of hundreds of neurons over many months while the animal is performing cognitive tasks such as memory encoding. We can also see the direct effects of cognition-affecting drugs such as antidepressants and antipsychotics in real time to correlate with neuronal network activity, allowing a whole new level of analysis and comprehension of brain phenomena.  This is super neat.

This project has several streams – it can be implemented for epilepsy, drug testing, dementia models, MS models etc. We would like to set up an epilepsy related project with miniscopes as an Honours/Masters/PhD project.



Faculty Research Themes

Neuroscience

School Research Themes

Neuroscience & Psychiatry



Research Opportunities

PhD students, Masters by Research, Honours students, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department / Centre

Medicine and Radiology

Research Node

Royal Melbourne Hospital

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