Using health-related quality of life scores as predictor of outcomes and to advance health economic evaluation methodologies in lower limb arthroplasty patients

Research Opportunity
St Vincent's Hospital
Group Leader Email Number Webpage
Michelle Dowsey Personal web page
Primary Supervisor Email Number Webpage
Philip Clarke Personal web page

Project Details

Patients undergoing lower limb surgeries are generally older patients with considerable co-morbidities hence their competing risk of death and potential surgery-related complications can be high. Although surgeries such as total knee replacements (TKR) have proven to be cost-effective treatments for end-stage osteoarthritis

  1. studies have shown that the cost of TKR can vary between patient subgroups; for example, TKR has been found to be more cost-effective in younger patients
  2. and those classified as low-risk based on age and co-morbidities
  3. Measuring value and understanding the cost of services is imperative in healthcare where providers are challenged to balance between the provision of quality care and to cost contain.

The St. Vincent’s Melbourne Arthroplasty Outcomes Registry (SMART) is a clinical registry which collects both clinical and patient reported outcomes in patients who have undergone elective lower limb arthroplasty at St. Vincent’s Hospital. The registry has recorded information on patient demographics, arthroplasty details and death for these patients since 1998. From 2006, the collection of patient reported HRQL was initiated and patients were followed-up at regular time intervals. Patients’ hospitalisation and surgery costs will be extracted from routinely collected administrative data at St. Vincent’s Hospital.

This project aims to use the registry data to demonstrate that health-related quality of life (HRQL) scores can be used to independently predict outcomes such as mortality, needed for revisions or surgery-related complications and to develop a risk assessment tool to assess outcomes in patients undergoing lower limb arthroplasty. These findings have the potential to add clinical value in informing the potential effectiveness and cost-effectiveness of the surgery in these patients.

School Research Themes


Research Opportunities

Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

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Research Group / Unit / Centre

Research Node

St Vincent's Hospital

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