Long-term Prognosis of Antiepilpetic Drug Therapy in People with Newly Diagnosed and Treated Epilepsy

Research Opportunity
PhD, Masters by Research, Honours, Master of Biomedical Science
Number of Honour Places Available
Medicine and Radiology
Royal Melbourne Hospital
Primary Supervisor Email Number Webpage
Professor Patrick Kwan patrick.kwan@unimelb.edu.au
Co-supervisor Email Number Webpage
Dr Ben Chen chen.z@unimelb.edu.au

Project Details

Antiepileptic drug is the mainstay of treatment modality for epilepsy. People with epilepsy often require lifelong antiepileptic drug treatment. Previous Glasgow study in 2000 demonstrated a-third of the epilepsy patient did not response well to antiepileptic drug therapy. Despite the introduction of more than a dozen new antiepileptic drugs in the past two decades, there remain no robust data to suggest improvement in treatment outcomes in the recent expanded Glasgow study. To valid the prognosis and antiepileptic drug response patterns observed in the Glasgow studies. We will assess treatment outcomes of 796 newly treated epilepsy patients who were seen at a First Seizure Clinic between 1 May 1999 and 31 May 2016 and were prospectively followed for up to 16 years in Australia. We will extract seizure, diagnostic and treatment information from baseline and follow-up

clinical documents and construct a digital database. The prognosis and response patterns in the Australia cohort will be compared with the findings in the Glasgow study.

Faculty Research Themes


School Research Themes

Neuroscience & Psychiatry

Research Opportunities

PhD, Masters by Research, Honours, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.


Medicine and Radiology

Research Node

Royal Melbourne Hospital

MDHS Research library
Explore by researcher, school, project or topic.