Investigating the role of novel proteins and genes in gestational diabetes
- Research Opportunity
- PhD, Masters by Research, Honours
- Number of Honour Places Available
- Number of Master Places Available
- Obstetrics and Gynaecology
- Royal Melbourne Hospital
|Associate Professor Martha Lappasemail@example.com||848 4370||Personal web page|
Summary This project aims will use our unique biobank of human clinical samples to thoroughly characterise the role of novel genes/proteins in the pathophysiology of gestational diabetes.
Gestational diabetes mellitus (GDM) complicates 15–20% of all pregnancies – a complication that reverberates into the future. The severe health and economic impacts of GDM can extend well beyond pregnancy and childbirth. The offspring of women with GDM are predisposed to an increased risk of metabolic and cardiovascular disease later in life. Despite the global health burden of gestational diabetes, the pathophysiology of the disease remains unclear, and therefore treatment options are limited. Our research has identified a number of genes and proteins that are dysregulated in gestational diabetes. Their role, however, in disease pathophysiology is not known.
This project aims will use our unique biobank of human clinical samples to thoroughly characterise the role of these genes/proteins in the pathophysiology of gestational diabetes. It is hoped that these biomolecules may be novel therapeutic target to reduce the incidence of GDM and its associated sequelae.
This project will use a range of laboratory methods including cell and tissue culture, molecular biology, enzyme immunoassays, and Western blot.
Faculty Research Themes
School Research Themes
PhD, Masters by Research, Honours
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
For further information about this research, please contact a supervisor.
Research Group / Unit / Centre
Research NodeRoyal Melbourne Hospital
MDHS Research library
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