In vitro brain tumour model – studying epileptic seizure development and sensitivity to anti-cancer therapy
- Research Opportunity
- PhD, Masters by Research, Honours, Master of Biomedical Science
- Number of Honour Places Available
- 2
- Department
- Medicine and Radiology
- Location
- Royal Melbourne Hospital
| Primary Supervisor | Number | Webpage | |
|---|---|---|---|
| Dr Chris French | frenchc@unimelb.edu.au | Personal web page |
| Co-supervisor | Number | Webpage | |
|---|---|---|---|
| Dr Rod Luwor | rluwor@unimelb.edu.au |
Project Details
Malignant brain tumours are notoriously difficult to treat and are often complicated by severe epilepticseizures. Research into therapies has been hampered by a limited range of model systems to explorepathogenesis and treatment of these tumours. We have developed an in vitro model of aggressive braintumours using a rat brain culture technique that actually develops epeileptic discharges. This uses severalwell-characterised human tumour cell lines as well as tumour “stem-cells” available in our laboratories.These are seeded into a section of brain maintained in tissue culture.The project has two aims – to examine the effects of conventional and novel treatments on the tumours aswell as the development of e
Faculty Research Themes
School Research Themes
Research Opportunities
PhD, Masters by Research, Honours, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
Key Contact
For further information about this research, please contact a supervisor.
Department
Research Node
Royal Melbourne HospitalMDHS Research library
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