Improving stroke outcome through brain monitoring and electrical stimulation

Research Opportunity
PhD, Honours, Master of Biomedical Science
Number of Honour Places Available
1
Number of Master Places Available
1
Department
Medical Bionics Department
Location
Bionics Institute
Primary Supervisor Email Number Webpage
Dr Carli Roulston carlir@unimelb.edu.au
Co-supervisor Email Number Webpage
A/Prof Chris Williams cwilliams@bionicsinstitute.org
Dr Matt Petoe mpetoe@bionicsinstitute.org

Summary Most strokes result in vary degrees of permanent brain injury due to a failure of neurons to re-grow at the injury site. This limitation in brain repair is often due to critical events such as inflammation that results in toxic signalling and formation of scar tissue that together create a major obstacle to brain repair and remodelling. Treatments that overcome these barriers may have greater success for recovery.

Project Details

Stroke affects ~60,000 Australians each year and is the second most common cause of death in Australia.  Most strokes result in vary degrees of permanent brain injury due to a failure of neurons to re-grow at the injury site. This limitation in brain repair is often due to critical events such as inflammation that results in toxic signalling and formation of scar tissue that together create a major obstacle to brain repair and remodelling. Treatments that overcome these barriers may have greater success for recovery.

Our laboratory is focused on investigating new treatments that promote recovery after stroke using pre-clinical animal models. In this project we will assess functional and anatomical responses to electrical brain stimulation and record changes in electrical brain activity after stroke, with/without stimulation, for correlation with treatment effects, to establish brain monitoring as a biomarker for treatment success. We will also determine how stimulation works and who is most likely to benefit. Knowledge from this project will directly inform future clinical trial design using our device for stroke, as well as provide useful information for treating other forms of brain injury.

https://www.florey.edu.au/science-research/research-teams/pre-clinical-stroke-research



Faculty Research Themes

Neuroscience

School Research Themes

Neuroscience & Psychiatry



Research Opportunities

PhD, Honours, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Medical Bionics Department

Research Node

Bionics Institute

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