Identification of additional markers of ferroptosis with mass spectrometry
- Research Opportunity
- PhD students, Masters by Research, Honours students
- Number of Honour Places Available
- Number of Master Places Available
- Department / Centre
- Baker Department of Cardiometabolic Health
- Baker Heart and Diabetes Institute
|Professor Peter Meiklefirstname.lastname@example.org||85321770||Personal web page|
|Dr Kevin Huynhemail@example.com||Personal web page|
Summary Interrogate the role of ether lipids (with antioxidant properties) in ferroptosis and their potential to mediate and regulate the process in various biological settings.
Ferroptosis is a specific form of cell death mediated by the accumulation of oxidised lipids. Several studies have highlighted this important process in relation to multiple diseases including cancer and neurodegeneration. While the biological mechanisms of lipid oxidation have been demonstrated to be a key factor, measurement of these lipid species is complicated in an in vivo setting. This project aims to identify and develop new ways of measuring molecules related to ferroptosis, using a combination of controlled in cell culture experiments and mass spectrometry assays. The assays developed will then be used to interrogate the role of ether lipids (with antioxidant properties) in ferroptosis and their potential to mediate and regulate the process in various biological settings.
Type of student: Honours, Masters or PhD. Particularly students that are technology/computation oriented with interest in cell culture.
School Research Themes
PhD students, Masters by Research, Honours students
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
For further information about this research, please contact a supervisor.
Department / Centre
Research NodeBaker Heart and Diabetes Institute
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