HPV immunity as markers of protection against infection

Research Opportunity
Honours, Master of Biomedical Science
Number of Honour Places Available
1
Number of Master Places Available
1
Department
Paediatrics
Location
Royal Children’s Hospital/Murdoch Childrens Research Institute
Primary Supervisor Email Number Webpage
Doctor Zheng Quan Toh zheng.quantoh@mcri.edu.au
Co-supervisor Email Number Webpage
Associate Professor Paul Licciardi paul.licciardi@mcri.edu.au Personal web page

Summary This project aims to examine the immunological response following HPV vaccination using a combination of techniques including flow cytometry, PCR and possibly RNA-sequencing.

Project Details

Cervical cancer is the fourth most common cancer in women worldwide, caused by infections with the human papillomavirus (HPV), with highest rates in low- and middle-income countries. Most cases (70%) are due to oncogenic HPV types 16 and 18 which are included in the two widely used prophylactic HPV vaccines, 2vHPV (Cervarix, GSK Biologicals) or 4vHPV (Gardasil, Merck) given as a 3-dose schedule over six months. We have recently completed a cohort study in Fijian girls who received 1, 2 or 3 doses of 4vHPV six years earlier and who subsequently were boosted with a dose of 2vHPV. This project aims to examine the immunological response following HPV vaccination using a combination of techniques including flow cytometry, PCR and possibly RNA-sequencing.



Faculty Research Themes

Child Health

School Research Themes

Child Health in Medicine



Research Opportunities

Honours, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Paediatrics

Research Node

Royal Children’s Hospital/Murdoch Childrens Research Institute

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