Functional role of VEZT over expression in endometrium
- Research Opportunity
- PhD students, Masters by Research, Honours students, Master of Biomedical Science
- Number of Honour Places Available
- 1
- Number of Master Places Available
- 1
- Department / Centre
- Obstetrics and Gynaecology
- Location
- Royal Women’s Hospital
| Primary Supervisor | Number | Webpage | |
|---|---|---|---|
| Dr Jacqueline Donoghue | jacqueline.donoghue@unimelb.edu.au | Personal web page |
Summary VEZT is the first protein coding gene that can be directly linked to increased susceptibility for endometriosis. At a population level, SNPs associated with an increased risk for endometriosis are also associated with increased VEZT expression in the endometrium. To date, it is unclear what functional role VEZT has in the development or progression of endometriosis. To generate new knowledge about VEZT and endometriosis, we have developed a novel mouse model that conditionally over-expresses VEZT ubiquitously including the reproductive system. Our primary aim is to characterise the impact increased expression VEZT has on fertility as well as endometrial lesion formation. This project will include working with an animal model of endometriosis, protein and molecular studies.
Project Details
School Research Themes
Research Opportunities
PhD students, Masters by Research, Honours students, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
Key Contact
For further information about this research, please contact a supervisor.
Department / Centre
Research Node
Royal Women’s HospitalMDHS Research library
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