Exploring the effects of human papillomavirus (HPV) vaccination on diversity of circulating genotypes

Research Opportunity
Masters by Research, Honours students
Number of Honour Places Available
1
Number of Master Places Available
1
Department / Centre
Obstetrics and Gynaecology
Location
Royal Women’s Hospital
Primary Supervisor Email Number Webpage
Dr Reza Haqshenas reza.haqshenas@unimelb.edu.au
Co-supervisor Email Number Webpage
Dr Gerald Murray gerald.murray@unimelb.edu.au
Dr Dorothy Machalek dmachalek@kirby.unsw.edu.au

Summary Human papillomavirus (HPV) infects 80% of sexually active people at least once in their lives. The virus causes several types of cancer in humans, including cervical cancer which causes over 570,000 new cases and 311,000 deaths annually, worldwide. HPV vaccination was introduced in 2007 and has led to dramatic reduction in circulating infections and related disease among vaccine eligible populations Our research group, located at the Royal Women’s Hospital, leads a number of HPV projects including 1) epidemiological studies of HPV vaccine impact and evaluation, 2) development of analytically sensitive diagnostic tests, 3) identification of new biomarkers for disease progression, and 4) understanding of molecular mechanisms of HPV-associated cancer. The prospective student will use a combination of molecular biology (nucleic acid extraction, conventional PCR, real time PCR, digital PCR, gene cloning, and sequencing) and epidemiological techniques to explore the effects of HPV vaccination on viral genotypes circulating in Australia using a unique clinical sample library collected pre- and post-HPV vaccination over the past 15 years.



Faculty Research Themes

Cancer, Infection and Immunology

School Research Themes

Cancer in Medicine, Women's Health



Research Opportunities

Masters by Research, Honours students
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department / Centre

Obstetrics and Gynaecology

Research Node

Royal Women’s Hospital

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