Exploring data from ENROLL-HD - an international observational study in Huntington’s disease

Research Opportunity
Honours, Master of Biomedical Science
Number of Honour Places Available
10
Department
Psychiatry
Group Leader Email Number Webpage
Dr Anita Goh goha@unimelb.edu.au 0418597375 Personal web page
Primary Supervisor Email Number Webpage
Dr Anita Goh gohan@unimelb.edu.au Personal web page

Project Details

Enroll-HD is a worldwide observational study for Huntington’s disease families. It monitors how the disease appears and changes over time in different people, and is open to people who either have HD or are at-risk. As of August 1st, there are a total of 16,565 active participants enrolled at 166 sites in 19 countries around the world. This project involves data mining of the third periodic dataset release—a set of de-identified records prepared for research that includes clinical, family history and genotyping data. This longitudinal dataset includes information from 8,714 people.
Opportunities:
* The opportunity to research what the student is interested in, as the dataset includes longitudinal medical information and results from tests of cognition, memory, physical ability and quality of life from individuals with the HD gene, those at risk, gene negative individuals, family controls, and community controls.  The data is a valuable resource to address a wide variety of research questions in Huntington’s disease, including psychiatric, cognitive, psychological, and lifestyle questions.   Discussion with supervisors will guide topic for the student.
* The project offers students an opportunity to develop research skills in a comprehensive international dataset, as well as develop skills in literature reviewing, data analysis, and epidemiological study skills
* Internationally renowned study and research team with international recognition.
* Dataset is already complete and accessible (thesis easily achievable in time frame)
* Publication of results in a peer-reviewed journal.


Faculty Research Themes

Neuroscience

School Research Themes

Neuroscience & Psychiatry



Research Opportunities

Honours, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Psychiatry


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