Examining brain structure in first-episode mania

Research Opportunity
Masters by Research, Honours, Master of Biomedical Science
Number of Honour Places Available
Group Leader Email Number Webpage
Dr Tamsyn Van Rheenen tamsyn.van@unimelb.edu.au Personal web page
Primary Supervisor Email Number Webpage
Dr Vanessa Cropley vcropley@unimelb.edu.au Personal web page

Project Details

While there is reasonable evidence to indicate that there are brain structural abnormalities in adults with bipolar disorder, far fewer studies have examined brain structure in individuals following a first episode of the illness. Characterizing brain structure at this early stage is important for determining whether brain changes are related to factors other than those associated with the manifest illness course. The aim of this project is to characterize differences in the structure of the brain in individuals in the early stage of the illness versus controls, using an available dataset comprising individuals who have been stabilised following a first episode of mania. The is expected to provide insight into the neurodevelopmental characteristics of bipolar disorder. A secondary question pertains to identifying whether longitudinal brain changes over a 12-month period are differentially affected by two commonly prescribed treatments for the illness.

The student will be responsible for conducting a literature review of the area, the development of the proposal and generation of study hypotheses, as well as data processing and statistical analyses. Publication of results is expected at the end of the project.

Faculty Research Themes


School Research Themes

Neuroscience & Psychiatry

Research Opportunities

Masters by Research, Honours, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.



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