Electrical Impedance changes during cochlear implantation

Research Opportunity
Honours, Master of Biomedical Science
Number of Honour Places Available
1
Department
Surgery
Location
Surgery, Otolaryngology, Royal Victorian Eye and Ear Hospital
Primary Supervisor Email Number Webpage
Dr Christofer Bester christofer.bester@unimelb.edu.au
Co-supervisor Email Number Webpage
Prof Stephen O'Leary sjoleary@unimelb.edu.au Personal web page
Dr Aaron Collins aaron.collins@unimelb.edu.au
Dr Hayden Eastwood haydente@unimelb.edu.au Personal web page

Summary We are pioneering the use of intra-operative monitoring of hearing function during cochlear implantation to actively preserve this function in the operating theatre. In this project, you will monitor the electrical impedance across the cochlear implant, while simultaneously measuring hearing function using electrocochleography.

Project Details

A goal a modern cochlear implantation is to protect any natural hearing the patients have prior to implantation. Despite advances in electrode design and “soft surgery” techniques, up to 70% of implant recipients lose this hearing. We are pioneering the use of intra-operative monitoring of hearing function during cochlear implantation to actively preserve this function in the operating theatre. In this project, you will monitor the electrical impedance across the cochlear implant, while simultaneously measuring hearing function using electrocochleography. We have demonstrated that changes in electrocochleography correlate strongly with post-operative losses of residual hearing, but we have not demonstrated the utility of electrode impedances measured during insertion. Part of this project is a retrospective analysis of existing data, with additional measurements in the operating theatre during cochlear implantation. The goal is to devise novel biomarkers indicating a reduction in hearing function, potentially due to cochlear trauma, and then the development of techniques to prevent or reverse this reduction. There is a significant possibility of translational results, from the bench to changes in clinical protocol.



Faculty Research Themes

Neuroscience



Research Opportunities

Honours, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Surgery

Research Node

Surgery, Otolaryngology, Royal Victorian Eye and Ear Hospital

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