Effects of Drugs on Cognition-Related Brain Wave Signals in the Rat
- Research Opportunity
- PhD, Masters by Research, Honours, Master of Biomedical Science
- Number of Honour Places Available
- 2
- Department
- Medicine and Radiology
- Location
- Royal Melbourne Hospital
| Primary Supervisor | Number | Webpage | |
|---|---|---|---|
| Dr Chris French | frenchc@unimelb.edu.au | Personal web page |
Summary In this project, signals related to cognitiveprocessing, including gamma frequency oscillations and place cells will be recorded with microelectrodearrays. The effects of antipsychotic drugs and some related compounds, including potassium and sodiumchannel modulators, will be examined
Project Details
It is increasingly recognised that the rhythmic signals recorded with the electroencephalogram (EEG), or“brain waves” are not just the “noise” of neural activity, but are probably frequency specific channels throughwhich cognition related signalling occurs, including memory encoding. High frequency (“gamma”) brainwave activity has been associated with cognitive activity in humans and animals, and is disrupted inpsychosis and schizophrenia.A largely neglected area of study in this area is the role of voltage-gated ion channels that have a significantrole in the generation of neuronal and network rhythmicity. In this project, signals related to cognitiveprocessing, including gamma frequency oscillations and place cells will be recorded with microelectrodearrays. The effects of antipsychotic drugs and some related compounds, including potassium and sodiumchannel modulators, will be examined
Faculty Research Themes
School Research Themes
Research Opportunities
PhD, Masters by Research, Honours, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
Key Contact
For further information about this research, please contact a supervisor.
Department
Research Node
Royal Melbourne HospitalMDHS Research library
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