Dose optimisation of antibiotics in children with cystic fibrosis

Research Opportunity
PhD students, Masters by Research
Number of Master Places Available
1
Department / Centre
Paediatrics
Location
Royal Children’s Hospital/Murdoch Childrens Research Institute
Primary Supervisor Email Number Webpage
Dr Amanda Gwee amanda.gwee@rch.org.au 9345 5522 Personal web page
Co-supervisor Email Number Webpage
Prof Sarath Ranganathan Sarath.Ranganathan@rch.org.au 9345 5522 Personal web page

Summary The aim of this project is to use pharmacokinetic and pharmacodynamic modelling to optimise antibiotic dosing in children with cystic fibrosis.

Project Details

The project involves:
(I) leading a multicentre prospective audit to collect blood samples in children with cystic fibrosis
(ii) using modelling to determine the pharmacokinetics (what happens to the drug in the body) and pharmacodynamics (the effect of the drug in the body) of antibiotics in children with CF. The model will then be used to simulate the antibiotic dose required to improve care for children with cystic fibrosis.


Faculty Research Themes

Child Health, Infection and Immunology

School Research Themes

Child Health in Medicine



Research Opportunities

PhD students, Masters by Research
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department / Centre

Paediatrics

Research Node

Royal Children’s Hospital/Murdoch Childrens Research Institute

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