Dose optimisation of antibiotics in children with cystic fibrosis
- Research Opportunity
- PhD students, Masters by Research
- Department / Centre
- Paediatrics
- Location
- Royal Children’s Hospital/Murdoch Childrens Research Institute
| Primary Supervisor | Number | Webpage | |
|---|---|---|---|
| Dr Amanda Gwee | amanda.gwee@rch.org.au | 9345 5522 | Personal web page |
| Co-supervisor | Number | Webpage | |
|---|---|---|---|
| Prof Sarath Ranganathan | Sarath.Ranganathan@rch.org.au | 9345 5522 | Personal web page |
Summary The aim of this project is to use pharmacokinetic and pharmacodynamic modelling to optimise antibiotic dosing in children with cystic fibrosis.
Project Details
The project involves:
(I) leading a multicentre prospective audit to collect blood samples in children with cystic fibrosis
(ii) using modelling to determine the pharmacokinetics (what happens to the drug in the body) and pharmacodynamics (the effect of the drug in the body) of antibiotics in children with CF. The model will then be used to simulate the antibiotic dose required to improve care for children with cystic fibrosis.
Faculty Research Themes
Child Health, Infection and Immunology
School Research Themes
Research Opportunities
PhD students, Masters by Research
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
Key Contact
For further information about this research, please contact a supervisor.
Department / Centre
Research Node
Royal Children’s Hospital/Murdoch Childrens Research InstituteMDHS Research library
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