Comparing the mental health and social determinants of family members who have HD in their family

Research Opportunity
PhD students, Masters by Research, Honours students, Post Doctor Researchers
Number of Honour Places Available
1
Department
Psychiatry
Location
Royal Melbourne Hospital
Primary Supervisor Email Number Webpage
Dr Samantha Loi samantha.loi@unimelb.edu.au 93428750 Personal web page
Co-supervisor Email Number Webpage
Dr Anita Goh goha@unimelb.edu.au 93428750 Personal web page
Professor Dennis Velakoulis dennis.velakoulis@mh.org.au 93428750

Summary We are interested in investigating the psychosocial outcomes and differences in sibling and family pairs who are gene positive and gene negative for Huntington's disease.

Project Details

Huntington's disease (HD) is a autosomal dominant neurodegenerative condition that has cognitive, motor and psychiatric manifestations, caused by an abnormal CAG expansion repeat. Those who are gene positive will eventually develop symptoms of this devastating disease. This knowledge in itself can be a precipitant for adverse mental health. However for those who are gene negative for HD may also experience mental health issues such as depression, anxiety and "survivor guilt". We are interested in comparing the mental health and other psychosocial outcome measures of matched sibling pairs and other family members who are gene positive and gene negative who are asymptomatic for the disease using a large registry containing data on people who are at genetic risk of HD.



Faculty Research Themes

Neuroscience

School Research Themes

Neuroscience & Psychiatry



Research Opportunities

PhD students, Masters by Research, Honours students, Post Doctor Researchers
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Psychiatry

Research Node

Royal Melbourne Hospital

MDHS Research library
Explore by researcher, school, project or topic.