Cognitive impairment and its interference with Activities of Daily Living

Research Opportunity
PhD, Masters by Research, Honours, Master of Biomedical Science
Number of Honour Places Available
Medicine and Radiology
Royal Melbourne Hospital
Primary Supervisor Email Number Webpage
Dr Julian Sacre 0393422635 Personal web page
Co-supervisor Email Number Webpage
Prof Andrea Maier 0393422635 Personal web page

Project Details

Dementia is a syndrome characterized by progressive cognitive decline and significant interference in daily function. The first observable problems in daily life often concern the instrumental activities of daily living (IADL). IADL can be defined as “complex activities for which multiple cognitive processes are necessary,” such as cooking, managing finances, and driving. Detecting functional decline along the continuum from normal aging to dementia is highly relevant for a number of reasons. First of all, subtle IADL problems may already be present in subjects with mild cognitive impairment (MCI) and predict progression to dementia. This suggests that assessment of IADL can be used to select MCI subjects at an increased risk for dementia. Once a diagnosis has been established, measuring IADL performance remains essential for the monitoring of clinical progression. Finally, IADL assessment plays a pivotal role in clinical trials, particularly in the evaluation of symptomatic treatment in dementia caused by Alzheimer's disease (AD).

This project aims to determine the trajectory of IADL in older individuals with and without cognitive impairment after an acute hospital admission.

Prerequisite: intention to improve epidemiological/statistical skills, intention to write a journal article, good communication skills, capacity to work in a multidisciplinary team.

Faculty Research Themes


School Research Themes

Neuroscience & Psychiatry, Ageing, Musculoskeletal

Research Opportunities

PhD, Masters by Research, Honours, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.


Medicine and Radiology

Research Group / Unit / Centre


Research Node

Royal Melbourne Hospital

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