CASE: Cartilage Analytic Screening Environment

Research Opportunity
PhD students, Masters by Research
Department / Centre
Surgery
Location
St Vincent's Hospital
Group Leader Email Number Webpage
A/Prof Claudia di Bella claudia.dibella@unimelb.edu.au Personal web page
Primary Supervisor Email Number Webpage
Dr Carmine Onofrillo carmine.onofrillo@unimelb.edu.au Personal web page
Co-supervisor Email Number Webpage
Dr Serena Duchi serena.duchi@unimelb.edu.au Personal web page
Prof Peter Choong pchoong@unimelb.edu.au Personal web page

Summary The goal of our research is to prevent the onset of Osteoarthritis by regenerating cartilage using a unique 3D printing technology, that requires multiple iteration steps to select the optimal combination of a biocompatible material and stem cells, to efficiently regenerate cartilage.

Project Details

The goal of our research is to prevent the onset of Osteoarthritis by regenerating cartilage using a unique 3D printing technology, that requires multiple iteration steps to select the optimal combination of a biocompatible material and stem cells, to efficiently regenerate cartilage.

The aim of this project is to generate a novel bio-physical tool to simultaneously monitor the biodegradation of a hydrogel material and the production of Collagen II matrix from stem cells. The tool will be used to discover novel materials for cartilage repair strategies.

This project will train the candidate in stem cells culturing, chondrogenic differentiation, DNA amplification and transfection, CRISPR/CAS9 technology, molecular and immunostaining analysis and fluorescence microscopy, 3D bioprinting, material science.

This project will provide an opportunity for a Master/PhD student to take part in a discovery project embedded in a multidisciplinary team based at the 3DBioFab@ACMD, St Vincent’s Hospital, Melbourne.


School Research Themes

Musculoskeletal



Research Opportunities

PhD students, Masters by Research
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department / Centre

Surgery

Research Group / Unit / Centre

Advanced Limb Reconstruction

Research Node

St Vincent's Hospital

MDHS Research library
Explore by researcher, school, project or topic.