Cartilage regeneration for in surgical 3D bioprinting

Research Opportunity
PhD students, Masters by Research, Honours students, Master of Biomedical Science
Number of Honour Places Available
1
Number of Master Places Available
1
Department / Centre
Surgery
Location
St Vincent's Hospital
Group Leader Email Number Webpage
A/Prof Claudia di Bella claudia.dibella@unimelb.edu.au Personal web page
Primary Supervisor Email Number Webpage
Dr Carmine Onofrillo carmine.onofrillo@unimelb.edu.au Personal web page
Co-supervisor Email Number Webpage
Dr Serena Duchi serena.duchi@unimelb.edu.au Personal web page
Prof Peter Choong pchoong@unimelb.edu.au Personal web page

Summary The goal of our research is to prevent the onset of Osteoarthritis by regenerating cartilage using a unique 3D printing technology, that requires multiple iteration steps to select the optimal combination of a biocompatible material and stem cells, to efficiently regenerate cartilage.

Project Details

The goal of our research is to prevent the onset of Osteoarthritis by regenerating cartilage using a unique 3D printing technology, that requires multiple iteration steps to select the optimal combination of a biocompatible material and stem cells, to efficiently regenerate cartilage.

With this project we aim to characterize in vitro and in human ex vivo models the characteristics of newly regenerated cartilage starting from 3D bioprinted stem cells once induced towards chondrogenic differentiation. In vitro and ex vivo models for evaluating cartilage repair/regeneration are of great value for transferring various culture systems into clinically relevant situations.

From this project the candidate will acquire skills and experience in stem cells culturing, 3D biopriting, perfusion bioreactors, molecular and immunostaining analyses, microCT imaging.

This project will provide opportunity for the student to take part in discovery and development process for future application of cartilage repair strategies in clinical settings.

This project is suited for a Honor/Master/PhD research project.

The experimental work for this project will be conducted at the 3DBioFab@ACMD, St.Vincent’s Hospital, Melbourne.


School Research Themes

Musculoskeletal



Research Opportunities

PhD students, Masters by Research, Honours students, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department / Centre

Surgery

Research Group / Unit / Centre

Advanced Limb Reconstruction

Research Node

St Vincent's Hospital

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