Can a common parasite alter brain injury outcomes?

Research Opportunity
PhD, Masters by Research, Honours, Master of Biomedical Science
Number of Honour Places Available
1
Department
Medicine and Radiology
Location
Royal Melbourne Hospital
Supervisor Email Number Webpage
Sandy Shultz sshultz@unimelb.edu.au 99030268 Personal web page

Project Details

Little is known about the effects of lifelong brain infections on the neurological health of the host. Toxoplasma gondii is a parasite infects approximately 1/3 of the world’s population and causes a chronic lifelong infection in the brain of the host. Toxoplasma is characterized by the presence of parasitic cysts within neurons, requiring a competent immune system to prevent parasite reactivation and encephalitis. In the immunocompetent individual, Toxoplasma infection is largely benign, however recent studies suggest a strong correlation with certain neurodegenerative disorders. Traumatic brain injury is a common neurodegenerative condition known to induce a robust immune response, however whether TBI outcomes differ in individuals who are infected by Toxoplasma gondii is not known. Therefore, here we will examine neuropathological and functional post-TBI outcomes in rodents that have or have not been infected by Toxoplasma gondii.




Research Opportunities

PhD, Masters by Research, Honours, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department

Medicine and Radiology

Research Node

Royal Melbourne Hospital

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