Can a common parasite alter brain injury outcomes?
- Research Opportunity
- PhD, Masters by Research, Honours, Master of Biomedical Science
- Number of Honour Places Available
- Medicine and Radiology
- Royal Melbourne Hospital
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Little is known about the effects of lifelong brain infections on the neurological health of the host. Toxoplasma gondii is a parasite infects approximately 1/3 of the world’s population and causes a chronic lifelong infection in the brain of the host. Toxoplasma is characterized by the presence of parasitic cysts within neurons, requiring a competent immune system to prevent parasite reactivation and encephalitis. In the immunocompetent individual, Toxoplasma infection is largely benign, however recent studies suggest a strong correlation with certain neurodegenerative disorders. Traumatic brain injury is a common neurodegenerative condition known to induce a robust immune response, however whether TBI outcomes differ in individuals who are infected by Toxoplasma gondii is not known. Therefore, here we will examine neuropathological and functional post-TBI outcomes in rodents that have or have not been infected by Toxoplasma gondii.
PhD, Masters by Research, Honours, Master of Biomedical Science
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research
For further information about this research, please contact a supervisor.
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