Brain mapping: Brain atlases with multiple topographic features

Research Opportunity
PhD students, Masters by Research, Post Doctor Researchers
Department / Centre
Royal Melbourne Hospital
Primary Supervisor Email Number Webpage
Associate Professor Andrew Zalesky +61390357747 Personal web page
Co-supervisor Email Number Webpage
Dr Ye Tian Personal web page

Summary Map innovative atlases of the human brain that incorporate multiple topographic features

Project Details

This project is about developing brain atlases that represent multiple topographic features, including discrete boundaries between regions, smooth gradients from one region to another, as well as more complex topographic structures. Current brain atlases invariably indicate only one feature—sharp regional boundaries—but we know that the brain exhibits a much richer set of topographic features. Topographic maps of land surfaces wouldn't be particularly useful if they only indicated one feature (e.g. waterways), but not landforms, vegetation and manmade structures!

Check out our recent research on a new technique called gradientography, which provides a principled approach to distinguish discrete boundaries in brain topography from gradients of continuous spatial variation. The latter are often misrepresented as discrete boundaries, resulting is brain atlases with spurious boundaries and over-parcellation. Further research is needed to investigate the fundamental topographic features that are needed to adequately map the topography of the human brain. This project aims to uncover the basic building blocks of brain topography and map new brain atlases that incorporate multiple topographic features.

Further research and key questions
  • Develop brain atlases that represent multiple topographic features, including boundaries, gradients and more complex topographic structures
  • What is the minimum set of topographic features that is needed to adequately represent brain topography?
Further reading

Faculty Research Themes


School Research Themes

Neuroscience & Psychiatry

Research Opportunities

PhD students, Masters by Research, Post Doctor Researchers
Students who are interested in joining this project will need to consider their elegibility as well as other requirements before contacting the supervisor of this research

Graduate Research application

Honours application

Key Contact

For further information about this research, please contact a supervisor.

Department / Centre


Research Node

Royal Melbourne Hospital

MDHS Research library
Explore by researcher, school, project or topic.